Other3

Iambic Therapeutics, Inc.

Total Value

$NaN

Filing Date

Oct 14, 2026

1 transactions

Trade Summary

On Oct 14, 2026, Manby Frederick R, Insider, reported $NaN of Iambic Therapeutics, Inc. (IAM) across 1 transactions. The filing covers company securities and reflects balanced net activity of $NaN. Insider transactions are sourced from SEC Form 4 disclosures and should be reviewed alongside company fundamentals and the insider's broader trading history.

Insider Information

Name: Manby Frederick R
Role: Insider
Location: SAN DIEGO, CA

Filing Details

Filing Date: Oct 14, 2026
Transaction Date: Oct 14, 2026
Accession Number: 0002156015-26-000003
Form Type: 3

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Footnotes

(F1)The option is subject to an early exercise provision and is immediately exercisable. Twenty-five percent of the shares subject to the option vested on March 1, 2024 and 1/48th of the shares vest monthly thereafter.
(F2)The shares subject to the option vest in 48 equal monthly installments beginning on July 1, 2023.
(F3)The option is subject to certain performance metrics. Prior to the date on which the reporting person became subject to Section 16, 50% of the shares subject to the option vested. The remaining 50% vest upon the Issuer's submission to the FDA of an IND application relating to cyclin-dependent kinase, as determined by the administrator of the Issuer's 2020 Equity Incentive Plan in accordance with the terms of the award.
(F4)The shares subject to the option vest in 48 equal monthly installments beginning on March 23, 2026.
(F5)The performance-based restricted stock units, or PSUs, vest upon the satisfaction of certain milestones and a liquidity event. The milestone requirement will be satisfied upon the earlier of (i) (a) the first dosing of a subject in a human clinical trial for the Issuer's product targeting HER2 ("HER2 Product"), together with prior data and information concerning such product, would be sufficient to support the filing of a Marketing Authorization Application in the U.S. or (b) a foreign clinical trial that is equivalent to clause (a), including any clinical trial indicated to be a Phase 3 trial, (ii) entering into a partnering transaction in which the Issuer grants to a non-affiliate third party exclusive rights to commercialize (or any co-commercialization rights in) a HER2 Product in the U.S. and/or European Union, or (iii) a change in control. The liquidity event was satisfied on October 14, 2026, the effective date of the Issuer's initial public offering of common stock.
(F6)The event deadline is March 3, 2033.
(F7)Each PSU represents a contingent right to receive one share of Issuer common stock.

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0104
Estimated average burden
hours per response:			0.5

1. Name and Address of Reporting Person^*

Manby Frederick R

(Last)

(First)

(Middle)

C/O IAMBIC THERAPEUTICS, INC.

5627 OBERLIN DRIVE, SUITE 120

(Street)

SAN DIEGO

92121

(City)

(State)

(Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
10/14/2026

3. Issuer Name and Ticker or Trading Symbol
Iambic Therapeutics, Inc. [ IAM ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	Chief Technology Officer

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	1,730,465	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivative Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
Employee Stock Option (right to buy)	⁽¹⁾	04/17/2033	Common Stock	39,083	$3	D
Employee Stock Option (right to buy)	⁽²⁾	08/07/2034	Common Stock	137,696	$6.47	D
Employee Stock Option (right to buy)	⁽³⁾	08/07/2034	Common Stock	137,697	$6.47	D
Employee Stock Option (right to buy)	⁽⁴⁾	03/03/2036	Common Stock	136,025	$8.73	D
Performance Share Units	⁽⁵⁾	⁽⁶⁾	Common Stock	317,394	⁽⁷⁾	D

Explanation of Responses:

1. The option is subject to an early exercise provision and is immediately exercisable. Twenty-five percent of the shares subject to the option vested on March 1, 2024 and 1/48th of the shares vest monthly thereafter.

2. The shares subject to the option vest in 48 equal monthly installments beginning on July 1, 2023.

3. The option is subject to certain performance metrics. Prior to the date on which the reporting person became subject to Section 16, 50% of the shares subject to the option vested. The remaining 50% vest upon the Issuer's submission to the FDA of an IND application relating to cyclin-dependent kinase, as determined by the administrator of the Issuer's 2020 Equity Incentive Plan in accordance with the terms of the award.

4. The shares subject to the option vest in 48 equal monthly installments beginning on March 23, 2026.

5. The performance-based restricted stock units, or PSUs, vest upon the satisfaction of certain milestones and a liquidity event. The milestone requirement will be satisfied upon the earlier of (i) (a) the first dosing of a subject in a human clinical trial for the Issuer's product targeting HER2 ("HER2 Product"), together with prior data and information concerning such product, would be sufficient to support the filing of a Marketing Authorization Application in the U.S. or (b) a foreign clinical trial that is equivalent to clause (a), including any clinical trial indicated to be a Phase 3 trial, (ii) entering into a partnering transaction in which the Issuer grants to a non-affiliate third party exclusive rights to commercialize (or any co-commercialization rights in) a HER2 Product in the U.S. and/or European Union, or (iii) a change in control. The liquidity event was satisfied on October 14, 2026, the effective date of the Issuer's initial public offering of common stock.

6. The event deadline is March 3, 2033.

7. Each PSU represents a contingent right to receive one share of Issuer common stock.

Remarks:

Exhibit 24.1 - Power of Attorney

	/s/ Sunny Chang, by power of attorney	10/14/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

Form 3 as rendered by the SEC from accession 0002156015-26-000003.

Iambic Therapeutics, Inc.

Trade Summary

Company Information

Insider Information

Filing Details

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Footnotes

SEC Form 3

SEC Filing

SEC Form 3