Sell4

BeOne Medicines Ltd.

ONC

Total Value

$12.4M

Net $11.3M sold

Filing Date

Oct 29, 2026

11 transactions

Sales

$11.3M

11 transactions

Trade Summary

On Oct 27, 2026, Wang Xiaodong, Director, sold $12.4M of BeOne Medicines Ltd. (ONC) across 11 transactions. The filing covers company securities and reflects net selling of $11.3M. Reported prices ranged from $36.90 to $366.22. Insider transactions are sourced from SEC Form 4 disclosures and should be reviewed alongside company fundamentals and the insider's broader trading history.

Price at the Time of the Trade

ONC daily price with the insider's sale marked at $362.97.

Sold near the 6-month high · the stock trades 2% higher today.

Price data is delayed and provided for context only — not investment advice.

Insider Information

Name: Wang Xiaodong
Role: Director

Filing Details

Filing Date: Oct 29, 2026
Transaction Date: Oct 27, 2026
Accession Number: 0001662982-26-000008
Form Type: 4
Net Trading Amount: -$11.3M

Non-Derivative Transactions

Date	Security	Shares	Price	Type	Value
Oct 27, 2026	ONC common stock	31,028	$36.90	Exercise	$1.1M
Oct 27, 2026	ONC common stock	880	$355.56	Sale	$312.9K
Oct 27, 2026	ONC common stock	1,440	$355.62	Sale	$512.1K
Oct 27, 2026	ONC common stock	1,239	$357.54	Sale	$443.0K
Oct 27, 2026	ONC common stock	1,681	$358.75	Sale	$603.1K
Oct 27, 2026	ONC common stock	1,280	$359.72	Sale	$460.4K
Oct 27, 2026	ONC common stock	320	$360.64	Sale	$115.4K
Oct 27, 2026	ONC common stock	2,331	$362.35	Sale	$844.6K
Oct 27, 2026	ONC common stock	8,148	$363.24	Sale	$3.0M
Oct 27, 2026	ONC common stock	2,841	$363.95	Sale	$1.0M
Oct 27, 2026	ONC common stock	3,965	$365.43	Sale	$1.4M
Oct 27, 2026	ONC common stock	6,903	$366.22	Sale	$2.5M

Derivative Transactions

Date	Security	Shares	Exercise Price	Type	Value
Oct 27, 2026	ONC derivative	403,364	—	Exercise	—

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Footnotes

(F1)These securities are held by a family trust, the beneficiaries of which are the Reporting Person's family members, for which the Reporting Person disclaims beneficial ownership.
(F2)These securities are held by Wang Investment LLC, of which 99% of the limited liability company interests are owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.
(F3)These securities are held by the spouse of the Reporting Person.
(F4)Each American Depositary Share represents 13 Ordinary Shares.
(F5)The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 9, 2026.
(F6)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.08 to $356.04, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F7)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.13 to $357.09, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F8)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.19 to $357.95, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F9)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.24 to $359.23, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F10)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.37 to $360.33, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F11)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.41 to $360.97, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F12)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $361.68 to $362.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F13)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $362.68 to $363.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F14)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $363.68 to $364.51, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F15)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $364.80 to $365.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F16)The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $365.88 to $366.45, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
(F17)The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.
(F18)These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Wang Xiaodong

(Last)

(First)

(Middle)

C/O BEONE MEDICINES I GMBH

AESCHENGRABEN 27, 21ST FLOOR

(Street)

BASEL

4051

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
BeOne Medicines Ltd. [ ONC ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)	X	Other (specify below)
			Chair, Scientific Advisory Brd

3. Date of Earliest Transaction (Month/Day/Year)
10/27/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Ordinary Shares								4,588,113	D
Ordinary Shares								1,025,063	I	See Footnote⁽¹⁾
Ordinary Shares								3,953,100	I	See Footnote⁽²⁾
Ordinary Shares								50	I	See Footnote⁽³⁾
American Depositary Shares⁽⁴⁾	10/27/2026		M		31,028	A	$36.9	31,028	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		880	D	$355.5595⁽⁶⁾	30,148	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		1,440	D	$355.616⁽⁷⁾	28,708	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		1,239	D	$357.5386⁽⁸⁾	27,469	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		1,681	D	$358.7462⁽⁹⁾	25,788	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		1,280	D	$359.7219⁽¹⁰⁾	24,508	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		320	D	$360.6363⁽¹¹⁾	24,188	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		2,331	D	$362.3503⁽¹²⁾	21,857	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		8,148	D	$363.242⁽¹³⁾	13,709	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		2,841	D	$363.9492⁽¹⁴⁾	10,868	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		3,965	D	$365.4293⁽¹⁵⁾	6,903	D
American Depositary Shares⁽⁴⁾	10/27/2026		S⁽⁵⁾		6,903	D	$366.2205⁽¹⁶⁾	0	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Share Option (Right to Buy)	$2.84⁽¹⁷⁾	10/27/2026		M			403,364	⁽¹⁸⁾	11/15/2026	Ordinary Shares	403,364	$0	0	D

Explanation of Responses:

1. These securities are held by a family trust, the beneficiaries of which are the Reporting Person's family members, for which the Reporting Person disclaims beneficial ownership.

2. These securities are held by Wang Investment LLC, of which 99% of the limited liability company interests are owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

3. These securities are held by the spouse of the Reporting Person.

4. Each American Depositary Share represents 13 Ordinary Shares.

5. The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 9, 2026.

6. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.08 to $356.04, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

7. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.13 to $357.09, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

8. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.19 to $357.95, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

9. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.24 to $359.23, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

10. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.37 to $360.33, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

11. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.41 to $360.97, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

12. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $361.68 to $362.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $362.68 to $363.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

14. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $363.68 to $364.51, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

15. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $364.80 to $365.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

16. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $365.88 to $366.45, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

17. The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

18. These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.

Remarks:

	/s/ Frank Collazo, as Attorney-in-Fact	10/29/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

Form 4 as rendered by the SEC from accession 0001662982-26-000008.

BeOne Medicines Ltd.

Trade Summary

Price at the Time of the Trade

Company Information

Insider Information

Filing Details

Non-Derivative Transactions

Derivative Transactions

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Footnotes

SEC Form 4

SEC Filing

Price at the Time of the Trade

SEC Form 4