Buy4

Adagene Inc.

ADAG

Total Value

$6.0K

Net $6.0K bought

Filing Date

Sep 25, 2026

1 transaction

Purchases

$6.0K

1 transaction

Trade Summary

On Sep 23, 2026, Tam Man Kin, Chief Financial Officer, Director, purchased $6.0K of Adagene Inc. (ADAG) across 1 transaction. The filing covers American Depositary Shares (ADSs) and reflects net buying of $6.0K. Reported prices ranged from $3.00. Insider transactions are sourced from SEC Form 4 disclosures and should be reviewed alongside company fundamentals and the insider's broader trading history.

Price at the Time of the Trade

ADAG daily price with the insider's purchase marked at $3.00.

Bought near the 6-month low · the stock trades 2% lower today.

Price data is delayed and provided for context only — not investment advice.

Insider Information

Name: Tam Man Kin
Role: Chief Financial Officer, Director

Filing Details

Filing Date: Sep 25, 2026
Transaction Date: Sep 23, 2026
Accession Number: 0001104659-26-111069
Form Type: 4
Net Trading Amount: $6.0K

Non-Derivative Transactions

Date	Security	Shares	Price	Type	Value
Sep 23, 2026	American Depositary Shares (ADSs)	2,000	$3.00	Purchase	$6.0K

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Footnotes

(F1)Including (i) 2,000 ADSs bought in the open market on 9/23/2026 at $3/ADS and (ii) vesting of Restricted Stock Unit (RSU) on 7/23/2026, which corresponds to 10,000 ADSs or 12,500 ordinary shares. Such RSU was granted under the 2021 Performance Incentive Plan in July 2024.
(F2)Such RSU was granted under the 2021 Performance Incentive Plan in July 2024. 12,500 ordinary shares or 10,000 ADSs of the remaining RSU shall vest on 7/23/2027 and 7/23/2028, respectively.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Tam Man Kin

(Last)

(First)

(Middle)

4F, BUILDING C14, NO. 218 XINGHU STREET

(Street)

SUZHOU JIANGSU

215123

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
Adagene Inc. [ ADAG ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	Chief Financial Officer

3. Date of Earliest Transaction (Month/Day/Year)
09/23/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
American Depositary Shares (ADSs)	09/23/2026		P		2,000	A	$3	12,000⁽¹⁾	D
Restricted Stock Unit								25,000⁽²⁾	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)

Explanation of Responses:

1. Including (i) 2,000 ADSs bought in the open market on 9/23/2026 at $3/ADS and (ii) vesting of Restricted Stock Unit (RSU) on 7/23/2026, which corresponds to 10,000 ADSs or 12,500 ordinary shares. Such RSU was granted under the 2021 Performance Incentive Plan in July 2024.

2. Such RSU was granted under the 2021 Performance Incentive Plan in July 2024. 12,500 ordinary shares or 10,000 ADSs of the remaining RSU shall vest on 7/23/2027 and 7/23/2028, respectively.

	/s/ Tam Man Kin	09/25/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

Form 4 as rendered by the SEC from accession 0001104659-26-111069.

Adagene Inc.

Trade Summary

Price at the Time of the Trade

Company Information

Insider Information

Filing Details

Non-Derivative Transactions

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Footnotes

SEC Form 4

SEC Filing

SEC Form 4

Price at the Time of the Trade