ORBIMED ADVISORS LLC
Total Volume
$294.4M
37 filings
Purchases
$135.0M
18 buy txns
Sales
$110.4M
29 sell txns
Net Activity
$24.7M
net bought
Profile
- Filings
- 37
- Buy transactions
- 18
- Sell transactions
- 29
- Companies
- 17
- Active
- 2025–2026
ORBIMED ADVISORS LLC, Director, 10% Owner, has filed 37 SEC reports (2025–2026), spread across 17 companies, totaling $294.4M in disclosed volume. Weighing $135.0M bought versus $110.4M sold, the history is a roughly balanced mix of buying and selling. The largest single open-market purchase on record is $34.9M in Braveheart Bio, Inc.. Data is sourced from official SEC Form 3, 4, and 5 filings.
Associated Companies
Sionna Therapeutics, Inc. (SION)
9 filings
$55.6M
Enliven Therapeutics, Inc. (ELVN)
2 filings
$51.7M
Shattuck Labs, Inc. (STTK)
4 filings
$45.5M
$5.5M bought
Braveheart Bio, Inc. (BRVE)
2 filings
$34.9M
$34.9M bought
Electra Therapeutics, Inc. (ETRA)
2 filings
$20.0M
$20.0M bought
ADARx Pharmaceuticals, Inc. (ADRX)
2 filings
$16.1M
$16.1M bought
Scribe Therapeutics, Inc. (SCTX)
2 filings
$15.0M
$15.0M bought
Q32 Bio Inc. (QTTB)
1 filing
$15.0M
$15.0M bought
Prelude Therapeutics Inc (PRLD)
1 filing
$12.5M
$12.5M bought
BlossomHill Therapeutics, Inc. (BLSM)
2 filings
$10.0M
$10.0M bought
Traws Pharma, Inc. (TRAW)
1 filing
$6.0M
$998.2K bought
Adicet Bio, Inc. (ACET)
2 filings
$5.7M
$5.0M bought
Keros Therapeutics, Inc. (KROS)
1 filing
$3.8M
PMV Pharmaceuticals, Inc. (PMVP)
2 filings
$2.4M
ImageneBio, Inc. (IMA)
2 filings
$208.9K
Yarrow Bioscience, Inc. (YARW)
1 filing
$0
Turnstone Biologics Corp. (TSBX)
1 filing
$0
Trading History
| Sep 30 | ADRX ADARx Pharmaceuticals, Inc. | ORBIMED ADVISORS LLC | Director, 10% Owner | Buy | $16.1M |
| Sep 24 | ADRX ADARx Pharmaceuticals, Inc. | ORBIMED ADVISORS LLC | Director, 10% Owner | Other | $0 |
| Sep 23 | ETRA Electra Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director, 10% Owner | Buy | $20.0M |
| Sep 18 | ETRA Electra Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Other | $0 |
| Aug 12 | BLSM BlossomHill Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Buy | $10.0M |
| Aug 11 | BRVE Braveheart Bio, Inc. | ORBIMED ADVISORS LLC | Director, 10% Owner | Buy | $34.9M |
| Aug 6 | BLSM BlossomHill Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Other | $0 |
| Aug 5 | BRVE Braveheart Bio, Inc. | ORBIMED ADVISORS LLC | Director, 10% Owner | Other | $0 |
| Jul 29 | YARW Yarrow Bioscience, Inc. | ORBIMED ADVISORS LLC | Director | Other | $0 |
| Jul 29 | SCTX Scribe Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Buy | $15.0M |
| Jul 23 | SCTX Scribe Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Other | $0 |
| Jul 9 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $3.9M |
| Jul 2 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $5.3M |
| Jun 24 | ELVN Enliven Therapeutics, Inc. | ORBIMED ADVISORS LLC | 10% Owner | Sell | $39.0M |
| Jun 17 | ELVN Enliven Therapeutics, Inc. | ORBIMED ADVISORS LLC | 10% Owner | Sell | $12.7M |
| Jun 15 | STTK Shattuck Labs, Inc. | ORBIMED ADVISORS LLC | Director | Other | $125 |
| Jun 9 | STTK Shattuck Labs, Inc. | ORBIMED ADVISORS LLC | Director | Conversion | $20.0M |
| Jun 1 | QTTB Q32 Bio Inc. | ORBIMED ADVISORS LLC | Director, 10% Owner | Buy | $15.0M |
| May 29 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $4.5K |
| May 11 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $13.4M |
| Apr 28 | TRAW Traws Pharma, Inc. | ORBIMED ADVISORS LLC | 10% Owner | Buy | $998.2K |
| Apr 23 | PRLD Prelude Therapeutics Inc | ORBIMED ADVISORS LLC | Director, 10% Owner | Buy | $12.5M |
| Apr 21 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $2.5M |
| Apr 16 | IMA ImageneBio, Inc. | ORBIMED ADVISORS LLC | Director | Other | $721 |
| Apr 16 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $22.9M |
| Apr 9 | ACET Adicet Bio, Inc. | ORBIMED ADVISORS LLC | 10% Owner | Sell | $674.8K |
| Feb 4 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $1.4M |
| Dec 29 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $1.5M |
| Dec 18 | KROS Keros Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Disposed | $3.8M |
| Nov 26 | SION Sionna Therapeutics, Inc. | ORBIMED ADVISORS LLC | Director | Sell | $4.8M |
| Oct 27 | PMVP PMV Pharmaceuticals, Inc. | ORBIMED ADVISORS LLC | 10% Owner | Sell | $1.5M |
| Oct 10 | ACET Adicet Bio, Inc. | ORBIMED ADVISORS LLC | 10% Owner | Buy | $5.0M |
| Sep 12 | PMVP PMV Pharmaceuticals, Inc. | ORBIMED ADVISORS LLC | 10% Owner | Sell | $900.0K |
| Sep 2 | STTK Shattuck Labs, Inc. | ORBIMED ADVISORS LLC | Director | Buy | $5.5M |
| Sep 2 | STTK Shattuck Labs, Inc. | ORBIMED ADVISORS LLC | Director | Other | $0 |
| Aug 12 | TSBX Turnstone Biologics Corp. | ORBIMED ADVISORS LLC | Director | Other | $0 |
| Jul 30 | IKNA ImageneBio, Inc. | ORBIMED ADVISORS LLC | Director | Grant | $208.2K |
37 filings