BAKER BROS. ADVISORS LP
Total Volume
$567.2M
34 filings
Purchases
$230.1M
156 buy txns
Sales
$319.1M
10 sell txns
Net Activity
-$89.0M
net sold
Profile
- Filings
- 34
- Buy transactions
- 156
- Sell transactions
- 10
- Companies
- 17
- Active
- 2025–2026
Across 34 filings between 2025–2026, BAKER BROS. ADVISORS LP has disclosed $567.2M in transactions — spread across 17 companies. Their disclosed trades are a roughly balanced mix of buying and selling — $230.1M in buys and $319.1M in sells. The largest single open-market purchase on record is $63.4M in Kodiak Sciences Inc.. Data is sourced from official SEC Form 3, 4, and 5 filings.
Associated Companies
Celcuity Inc. (CELC)
3 filings
$327.3M
$9.6M bought
Kodiak Sciences Inc. (KOD)
4 filings
$158.4M
$157.0M bought
MADRIGAL PHARMACEUTICALS, INC. (MDGL)
3 filings
$63.5M
$61.9M bought
INCYTE CORP (INCY)
5 filings
$6.3M
Kiniksa Pharmaceuticals International, plc (KNSA)
1 filing
$3.5M
Entrada Therapeutics, Inc. (TRDA)
2 filings
$1.6M
$1.6M bought
ACADIA PHARMACEUTICALS INC (ACAD)
1 filing
$1.4M
Kymera Therapeutics, Inc. (KYMR)
1 filing
$1.2M
KALA BIO, Inc. (KALA)
1 filing
$1.1M
Denali Therapeutics Inc. (DNLI)
2 filings
$778.8K
Replimune Group, Inc. (REPL)
2 filings
$677.6K
BICYCLE THERAPEUTICS PLC (BCYC)
1 filing
$538.1K
vTv Therapeutics Inc. (VTVT)
2 filings
$446.7K
Prelude Therapeutics Inc (PRLD)
2 filings
$299.7K
BeOne Medicines Ltd. (ONC)
2 filings
$262.0K
DBV Technologies S.A. (DBVT)
1 filing
$0
IGM Biosciences, Inc. (IGMS)
1 filing
$0
Trading History
| Oct 2 | INCY INCYTE CORP | BAKER BROS. ADVISORS LP | Insider | Grant | $0 |
| Sep 30 | KOD Kodiak Sciences Inc. | BAKER BROS. ADVISORS LP | Insider | Buy | $35.0M |
| Sep 30 | KOD Kodiak Sciences Inc. | BAKER BROS. ADVISORS LP | Insider | Buy | $63.4M |
| Sep 30 | KOD Kodiak Sciences Inc. | BAKER BROS. ADVISORS LP | Insider | Buy | $58.6M |
| Aug 11 | REPL Replimune Group, Inc. | BAKER BROS. ADVISORS LP | Insider | Other | $274 |
| Jul 16 | CELC Celcuity Inc. | BAKER BROS. ADVISORS LP | Insider | Sell | $317.8M |
| Jul 2 | KOD Kodiak Sciences Inc. | BAKER BROS. ADVISORS LP | Insider | Award | $1.4M |
| Jun 29 | VTVT vTv Therapeutics Inc. | BAKER BROS. ADVISORS LP | Insider | Award | $421.0K |
| Jun 25 | KYMR Kymera Therapeutics, Inc. | BAKER BROS. ADVISORS LP | Insider | Award | $1.2M |
| Jun 18 | MDGL MADRIGAL PHARMACEUTICALS, INC. | BAKER BROS. ADVISORS LP | Insider | Grant | $1.5M |
| Jun 15 | ONC BeOne Medicines Ltd. | BAKER BROS. ADVISORS LP | Insider | Grant | $0 |
| Jun 10 | PRLD Prelude Therapeutics Inc | BAKER BROS. ADVISORS LP | Insider | Award | $299.4K |
| Jun 10 | INCY INCYTE CORP | BAKER BROS. ADVISORS LP | Insider | Grant | $1.2M |
| Jun 5 | DNLI Denali Therapeutics Inc. | BAKER BROS. ADVISORS LP | Insider | Grant | $756.0K |
| Jun 2 | ACAD ACADIA PHARMACEUTICALS INC | BAKER BROS. ADVISORS LP | Insider | Grant | $1.4M |
| Jun 2 | KNSA Kiniksa Pharmaceuticals International, plc | BAKER BROS. ADVISORS LP | Insider | Grant | $3.5M |
| May 27 | ONC BeOne Medicines Ltd. | BAKER BROS. ADVISORS LP | Insider | Sell | $262.0K |
| May 11 | INCY INCYTE CORP | BAKER BROS. ADVISORS LP | Insider | Exercise | $5.1M |
| Apr 22 | PRLD Prelude Therapeutics Inc | BAKER BROS. ADVISORS LP | Insider | Other | $225 |
| Apr 7 | REPL Replimune Group, Inc. | BAKER BROS. ADVISORS LP | Insider | Award | $677.3K |
| Apr 2 | INCY INCYTE CORP | BAKER BROS. ADVISORS LP | Insider | Grant | $0 |
| Jan 14 | DBVT DBV Technologies S.A. | BAKER BROS. ADVISORS LP | Insider | Exercise | $0 |
| Jan 6 | BCYC BICYCLE THERAPEUTICS PLC | BAKER BROS. ADVISORS LP | Insider | Grant | $538.1K |
| Dec 15 | DNLI Denali Therapeutics Inc. | BAKER BROS. ADVISORS LP | Insider | Other | $22.9K |
| Nov 24 | TRDA Entrada Therapeutics, Inc. | BAKER BROS. ADVISORS LP | Insider | Buy | $261.8K |
| Nov 12 | TRDA Entrada Therapeutics, Inc. | BAKER BROS. ADVISORS LP | Insider | Buy | $1.4M |
| Oct 2 | KALA KALA BIO, Inc. | BAKER BROS. ADVISORS LP | Insider | Sell | $1.1M |
| Oct 2 | INCY INCYTE CORP | BAKER BROS. ADVISORS LP | Insider | Grant | $0 |
| Sep 10 | CELC Celcuity Inc. | BAKER BROS. ADVISORS LP | Insider | Buy | $9.6M |
| Sep 5 | VTVT vTv Therapeutics Inc. | BAKER BROS. ADVISORS LP | Insider | Grant | $25.7K |
| Aug 20 | MDGL MADRIGAL PHARMACEUTICALS, INC. | BAKER BROS. ADVISORS LP | Insider | Buy | $36.9M |
| Aug 20 | MDGL MADRIGAL PHARMACEUTICALS, INC. | BAKER BROS. ADVISORS LP | Insider | Buy | $25.0M |
| Aug 18 | IGMS IGM Biosciences, Inc. | BAKER BROS. ADVISORS LP | Insider | Other | $0 |
| Aug 1 | CELC Celcuity Inc. | BAKER BROS. ADVISORS LP | Insider | Other | $0 |
34 filings