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Opaleye Management Inc.
10% OwnerCIK 0001595855
Total Volume
$32.7M
50 filings
Purchases
$15.7M
98 buy txns
Sales
$16.9M
24 sell txns
Net Activity
-$1.2M
net sold
Profile
- Filings
- 50
- Buy transactions
- 98
- Sell transactions
- 24
- Companies
- 6
- Active
- 2026
Opaleye Management Inc., 10% Owner, has filed 50 SEC reports (2026), spread across 6 companies, totaling $32.7M in disclosed volume. Weighing $15.7M bought versus $16.9M sold, the history is a roughly balanced mix of buying and selling. The largest single open-market purchase on record is $2.9M in Sol-Gel Technologies Ltd.. Data is sourced from official SEC Form 3, 4, and 5 filings.
Associated Companies
Trading History
50 loaded
| Oct 26 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $158.6K |
| Oct 26 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $265.8K |
| Oct 21 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $8.0K |
| Oct 19 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $308.6K |
| Oct 16 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $136.2K |
| Oct 13 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $29.7K |
| Oct 5 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $123.8K |
| Oct 1 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $16.4K |
| Oct 1 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $31.7K |
| Sep 28 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $270.8K |
| Sep 23 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $31.7K |
| Sep 16 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $1.1M |
| Sep 14 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $207.4K |
| Sep 10 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $31.9K |
| Sep 9 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $687.2K |
| Sep 3 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $116.5K |
| Aug 31 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $2.8M |
| Aug 19 | GRCE Grace Therapeutics, Inc. | Opaleye Management Inc. | 10% Owner | Buy | $24.2K |
| Aug 14 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $68.0K |
| Aug 4 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $423.0K |
| Jul 28 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $1.0K |
| Jul 24 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $1.6M |
| Jul 17 | ETON Eton Pharmaceuticals, Inc. | Opaleye Management Inc. | 10% Owner | Sell | $1.1M |
| Jul 16 | ETON Eton Pharmaceuticals, Inc. | Opaleye Management Inc. | 10% Owner | Sell | $1.1M |
| Jul 15 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $124.8K |
| Jul 10 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $39.0K |
| Jul 7 | ETON Eton Pharmaceuticals, Inc. | Opaleye Management Inc. | 10% Owner | Sell | $4.8M |
| Jul 2 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $123.2K |
| Jun 29 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $976.5K |
| Jun 15 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $45.8K |
| Jun 11 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $183.7K |
| Jun 9 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $58.6K |
| May 29 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $434.7K |
| May 19 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $196.0K |
| May 14 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $231.5K |
| May 4 | SNWV SANUWAVE Health, Inc. | Opaleye Management Inc. | 10% Owner | Sell | $574.2K |
| Apr 30 | SNWV SANUWAVE Health, Inc. | Opaleye Management Inc. | 10% Owner | Sell | $1.3M |
| Apr 21 | SNWV SANUWAVE Health, Inc. | Opaleye Management Inc. | 10% Owner | Sell | $337.0K |
| Mar 31 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $60.0K |
| Mar 26 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $108.6K |
| Mar 24 | SLGL Sol-Gel Technologies Ltd. | Opaleye Management Inc. | 10% Owner | Buy | $2.9M |
| Mar 20 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $26.2K |
| Mar 18 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $7.7K |
| Mar 13 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $75.7K |
| Mar 6 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $387.6K |
| Mar 5 | HROW HARROW, INC. | Opaleye Management Inc. | 10% Owner | Sell | $7.8M |
| Mar 4 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $411.6K |
| Mar 2 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $25.3K |
| Feb 24 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Buy | $1.0M |
| Feb 20 | ACOG Alpha Cognition Inc. | Opaleye Management Inc. | 10% Owner | Other | $0 |
50 filings+